Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1995-06-02
2000-09-19
McElwain, Elizabeth F.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 911, 435468, 536 231, 536 2371, 800298, 8003201, C12N 1582, C12N 1509, C12N 1532
Patent
active
061210145
ABSTRACT:
DNA sequences optimized for expression in plants are disclosed. The DNA sequences preferably encode for an insecticidal polypeptides, particularly insecticidal proteins from Bacillus thuringiensis. Plant promoters, particular tissue-specific and tissue-preferred promoters are also provided. Additionally disclosed are transformation vectors comprising said DNA sequences. The transformation vectors demonstrate high levels of insecticidal activity when transformed into maize.
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Murray et al., "Condon usage in plant genes", Nucleic Acids Research, 17(2):477-498 (1989).
Perlack et al., "Modification of the coding sequence enchances plant expression of insect control protein genes", Proc. Natl. Acad. Sci. USA, 88:3324-3328 (1991).
Vaeck et al., "Transgenic plants protected from insect attack", Nature, 328:33-37 (1987).
Desai Nalini M.
Koziel Michael G.
Lewis Kelly S.
McElwain Elizabeth F.
Meigs J. Timothy
Novartis Finance Corporation
Pace Gary M.
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