Method for producing a collagen hydrogel

Details Method for producing a collagen hydrogel Method for producing a collagen hydrogel

1990-12-06

1992-05-19

Lowe, James

Plastic and nonmetallic article shaping or treating: processes

Optical article shaping or treating

264 14, 264 26, 264 22, 264 28, 264 41, 264233, 264330, 522 87, 523105, 523106, 523114, 523449, B29D 1100, C08H 100

Patent

active

051146274

ABSTRACT:
A method of making a collagen-hydrogel is shown. The method comprises the steps of forming a radical free polymer of a hydrophilic monomer; mixing the hydrophilic monomer with a stock solution of collagen in the presence of a weak solution of ammonium persulfate and sodium metabisuleate forming a clear viscous monomer solution; and heating said viscous monomer solution in the presence of a crosslinking agent to polymerize the same into a three dimensional polymeric meshwork having collagen from the stock solution of collagen interdispersed within the three dimensional polymeric meshwork.

REFERENCES:
patent: 4388428 (1983-06-01), Kuzma et al.
patent: 4452776 (1984-06-01), Reforjo
patent: 4452925 (1984-06-01), Kuzma et al.

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