Method for producing 5'-nucleotide

Details Method for producing 5'-nucleotide Method for producing 5'-nucleotide

1995-05-10

1997-04-22

Wilson, James O.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 2672, 536 2673, 536 2674, 536 268, C07H 100, C07H 1906, C07H 1916

Patent

active

056230699

ABSTRACT:
A method of producing 5'-nucleotide, which comprises maintaining a nucleoside suspension in an organic solvent at a temperature not lower than about 20.degree. C., and then subjecting the resultant suspension to a phosphorylatipon of the nucleoside(s).
According to the present invention, 5'-nucleotide can be produced from a nucleoside at high purity and high yield in a shortened reaction time, and impurity removal in the nucleotide purification process is easily accomplished.

REFERENCES:
patent: 3413282 (1968-11-01), Yoshikawa et al.
patent: 3433783 (1969-03-01), Honja et al.
patent: 3444158 (1969-05-01), Honjo et al.

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