Method for producing 3,4-dihydroxyphthalic acid

Details Method for producing 3,4-dihydroxyphthalic acid Method for producing 3,4-dihydroxyphthalic acid

1995-03-21

1996-06-04

Lilling, Herbert J.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing oxygen-containing organic compound

4352521, 435146, C12P 744, C12P 742

Patent

active

055232205

ABSTRACT:
There is disclosed a method for producing 3,4-dihydroxyphthalic acid, comprising treating phthalic acid with a product which is obtained by treating the cell membrane fraction of microorganism bacterial bodies capable of converting phthalic acid to 3,4-dihydroxyphthalic acid with a condensate of polyethylene oxide with a higher alcohol, thereby converting the phthalic acid to 3,4-dihydroxyphthalic acid. According to the method, only 3,4-dihydroxyphthalic acid, which is an intermediary metabolite, can be produced efficiently in a process of biodegrading phthalic acid with a microorganism.

REFERENCES:
patent: 5135858 (1992-08-01), Yamada et al.
Eaton et al "Jour of Bacteriol" Jul. 1982 vol. 151, No. 1 pp. 48-57 Metabolism of Dibutylphthalate & Phthalate by Micrococcus sp. Strain 12B.

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