Method for producing 2-methylspiro(1,3-oxathiolane-5,3')quinucli

Details Method for producing 2-methylspiro(1,3-oxathiolane-5,3')quinucli Method for producing 2-methylspiro(1,3-oxathiolane-5,3')quinucli

1995-05-11

1996-11-05

Ford, John M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D45302

Patent

active

055719180

ABSTRACT:
A method for producing 2-methylspiro(1,3-oxathiolane-5,3')quinuclidine, which comprises reacting 3-hydroxy-3-mercaptomethylquinuclidine or a salt thereof and a carbonyl compound in the presence of a catalyst made of at least one member selected from the group consisting of tin halides, oxyacids of phosphorus, phosphorus oxyhalides and organic sulfonic acids, to produce cis-form 2-methylspiro(1,3-oxathiolane-5,3')quinuclidine or a salt thereof.

REFERENCES:
patent: 4861886 (1989-08-01), Haga et al.

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