Method for producing 2-hydroxy-4-(methylthio)butyric acid

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...

Reexamination Certificate

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C435S130000

Reexamination Certificate

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07632664

ABSTRACT:
A method for producing 2-hydroxy-4-(methylthio)butyric acid which comprises the following steps (A), (B) and (C):Step (A): step of reacting 1,2-epoxy-3-butene with water to obtain 3-butene-1,2-diol,Step (B): step of reacting 3-butene-1,2-diol with methanethiol to obtain 4-(methylthio)butane-1,2-diol,Step (C): step of oxidizing 4-(methylthio)butane-1,2-diol to obtain 2-hydroxy-4-(methylthio)butyric acid.

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Steadman, Thomas R. et al., “A Methionine Substitute: 4-Methylthiobutane-1,2-diol”, J. Agric Food Chem, vol. 23, No. 6, pp. 1137-1114, 1975.

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