Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Implantable prosthesis
Patent
1994-07-15
1996-01-02
Prebilic, Paul B.
Prosthesis (i.e., artificial body members), parts thereof, or ai
Implantable prosthesis
606151, 606152, 600 37, A61F 202
Patent
active
054804361
ABSTRACT:
A device for preventing adhesions or binding of tissue to tissue or of tissue to bone which comprises a composite of a first layer and a second layer, each of which comprises a biodegradable polymer, such as, for example, a polyethylene glycol/polybutylene terephthalate copolymer. The first layer is selected from the group consisting of a non-porous layer and a porous layer having a pore size no greater than 3.mu.. The second layer has pores which have a pore size of from about 30.mu. to about 250.mu.. The device is placed between two tissues or between tissue and bone. Such a composite device provides for tissue growth into the second layer, while the first layer acts as an adhesion-preventing barrier, and enables attachment of the device to tissue without suturing. Alternatively, the device comprises the first layer hereinabove mentioned and a second layer which is an adherence layer and which adheres to tissue and/or bone.
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Gilding et al, "Biodegradable Polymers for use in surgery-poly (ethylene oxide) poly (ethylene terephthalate) (PEO/PET) copolymers", Polymer, vol. 20, Dec. 1979, pp. 1454-1458.
Lawson et al., "Lamina Repair and Replacement to Control Laminectomy Membrane Formation in Dogs", Spine, vol. 16, No. 6, (1991), pp. S222-S226.
Bakker Dirkjan
Bakkum Erica A.
van Blitterswlijk Clemens A.
Lillie Raymond J.
Olstein Elliot M.
Osteotech Inc.
Prebilic Paul B.
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