Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...
Patent
1992-10-28
1994-08-02
Stoll, Robert L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Phosphorus containing other than solely as part of an...
A61K 3166
Patent
active
H00013455
ABSTRACT:
A method is provided for blocking or preventing the prenylation of CXXX box containing proteins thereby preventing and/or treating hepatitis D which includes the step of administering a therapeutically effective amount of a protein-prenyl transferase inhibitor.
REFERENCES:
patent: 4871721 (1989-10-01), Biller
patent: 5025003 (1991-06-01), Biller
patent: 5157027 (1992-10-01), Biller et al.
Glenn, Jeffrey S. et al, "Identification of a Prenylation Site in Delta Virus Large Antigen", Science, vol. 256, pp. 1331-1333, May 29, 1992.
Anthony Joseph D.
Bristol--Myers Squibb Company
Rodney Burton
Stoll Robert L.
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