Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Patent
1983-12-02
1985-10-08
Meyers, Albert T.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
8161, A61K 31165, A61K 7155
Patent
active
045461120
ABSTRACT:
A method for preventing or reducing dermal irritation caused by thioglycolate depilatories by applying capsaicin and/or its salt(s) to at least a portion of the depilated area.
REFERENCES:
patent: 3628910 (1971-12-01), Grayson
patent: 4121904 (1978-10-01), Schampol
patent: 4313958 (1982-02-01), LaHann
patent: 4401663 (1983-08-01), Buckwalter et al.
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Kiernan, "A Study of Chemically Induced Acute Inflammation in the Skin of the Rat" Quart. J. Exp. Physiol., vol. 62, (1977), pp. 151-161.
Jansco et al., "Direct Evidence for Neurogenic Inflammation and its Prevention by Denervation and by Pretreatment with Capsaicin," Br. J. Pharm. Chemother., vol. 31, (1967), pp. 138-151.
Ariver et al., "Modification by Capsaicin and Compound 40/80 of Dye Leakage Induced by Irritants in the Rat," Br. J. Pharm., vol. 59, (1977), pp. 61-68.
Yaksh et al., "Intrathecal Capsaicin Depletes Substance P in the Rat Spinal Cord and Produces Prolonged Thermal Analgesia," Science, vol. 260, (1979), pp. 481-483.
Virus et al., "Pharmacologic Actions of Capsaicin: Apparent Involvement of Substance P and Serotonin," Life Sciences, vol. 24, (1979), pp. 1273-1281.
Bernstein et al., "Bradykinin, Substance P, Prostaglandin E.sub.2 and Papain Induced Flare Suppressed by Capsaicin," Clin. Res., vol. 29, No. 4, (1981), p. 787A.
Farmer Ralph W.
LaHann Thomas R.
Abramson Freda
Dabbiere David K.
Goldstein Steven J.
Guttag Eric W.
Meyers Albert T.
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