Method for preventing onset of restenosis after angioplasty empl

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514345, 514365, 514398, 514400, 514448, 514461, 514568, 514569, A61K 3144, A61K 31425, A61K 31415, A61K 3138, A61K 3119

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active

060341106

ABSTRACT:
A method is provided for preventing or reducing the risk of restenosis following angioplasty by administering a retinoid, such as an RXR-selective retinoid, e.g. the compound of the formula: ##STR1## and a PPAR.gamma. specific ligand and pharmaceutically acceptable salts and esters and amides thereof.

REFERENCES:
patent: 5116864 (1992-05-01), March et al.
patent: 5140012 (1992-08-01), McGovern et al.
patent: 5166143 (1992-11-01), Ondetti et al.
patent: 5213561 (1993-05-01), Weinstein et al.
patent: 5455265 (1995-10-01), Chandraratna
Serruys et al, "Incidence of restenosis after successful coronary angioplasty: a time-related phenomenon. A quantitative angiographic study in 342 consecutive patients at 1,2,3, and 4 months" Therapy and Prevention-Coronary Angioplasty; vol. 77, No. 2, Feb. 1988; pp. 361-371.
Schoojans et al, "The peroxisome proliferator activated receptors (PPARs) and their effects on lipid metabolism and adipocyte differentiation"; Biochimica Biophysica Acta; 1302 (1996); pp. 93-109.
Dubey et al, "Pioglitazone attenuates hypertension and inhibits growth of renal arteriolar smooth muscle in rats", Am. J. Physiol., Oct. 1993; pp. R726-32.

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