Method for preventing coloration of aqueous preparations of cefm

Details Method for preventing coloration of aqueous preparations of cefm Method for preventing coloration of aqueous preparations of cefm

1987-06-15

1989-02-28

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Boron containing doai

514201, 514912, A61K 3169, A61K 31545

Patent

active

048085774

ABSTRACT:
Incorporation of boric acid or a salt thereof in an aqueous preparation containing cefmenoxime or a salt thereof is effective in the prevention of coloration of the preparation.
Therefore, cefmenoxime and its salts can be used as aqueous ophthalmic, otic or nasal drugs for topical application.

REFERENCES:
patent: 4098888 (1978-07-01), Ochiai et al.
patent: 4551456 (1985-11-01), Katz
The Merck Index, Tenth Edition, p. 269 (1983).

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