Method for preventing chemical crosstalk in enzyme-linked...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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C506S011000, C506S042000, C506S043000

Reexamination Certificate

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07838261

ABSTRACT:
A method for biochemical analysis uses a micro-reaction array with at least two reaction chambers for materials which react together chemically or biochemically. The reaction chambers are smaller than 1 μl, the reaction chambers are filled together by throughflow, the chemical or biochemical reactions of the substances retained therein then occurs in the individual isolated reaction chambers, thus preventing an interference between the reactions in the individual reaction chambers and the reaction products remain enclosed in the relevant reaction chambers. In the system the planar array has at least two reaction chambers for substances, whereby the reaction chambers are closed with the goal of preventing an exchange of substances.

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patent: WO01/34842 (2001-05-01), None
Proudnikov et al 1998 Anal. Biochem 259:34-41.
Molekularbiologie der Zelle, 1997, 3A, p. 216, Methoden der Zellforschung, VCH Weinheim.
Paeschke et al., “A Stacked Multichannel Amperometric Detection System”, Proceedings of the μTAS 94, Workshop, 1994, pp. 249-254, Kluver Academic Publishers.
Abstract of German Patent Publication No. DE19736641, published on Mar. 11, 1999.

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