Liquid purification or separation – Processes – Liquid/liquid solvent or colloidal extraction or diffusing...
Patent
1988-10-24
1990-07-03
Jones, W. Gary
Liquid purification or separation
Processes
Liquid/liquid solvent or colloidal extraction or diffusing...
210647, 604 5, B01D 6124
Patent
active
049388738
ABSTRACT:
The introduction of Defibrotide, as a bolus or by infusion, upstream of the dialysis membrane of the extra body circuit of apparatus for the extra-body dialysis prevents coaguli from being formed in the blood stream.
REFERENCES:
patent: 3770720 (1973-11-01), Butti et al.
patent: 3829567 (1974-08-01), Butti et al.
patent: 3865726 (1975-02-01), Chibata et al.
patent: 3899481 (1975-08-01), Butti et al.
patent: 3946731 (1976-03-01), Lichtenstein
patent: 4649134 (1987-03-01), Bonomini
patent: 4693995 (1987-09-01), Prino et al.
C. Mion et Alii: "Haemodialysis without Herparin, a Possible Benefit from Use of Ticlopidine in End Stage Renal Disease Haemodialysis Patients", Thromb. and Haemostas. 46 262, 1981.
S. M. Rajah et Alii: "Evaution of Five Antiplatelet Regimens in Haemodialysis: Prevention of Platelet Deposition and Thrombus Formation", Thromb and Haemostas. 50 61, 1983.
Chronique OMS liste 21 (Suppl. to n. 5 vol. 35 1981).
S. Cocheri et alii: "Effect of Fibrinolysis on a New Antithrombotic Agent: Franction P (Defibrotide). A Multicenter Trial", Int. J. Clin. Pharm. Res. II (3) 227-245, 1982.
G. Prino et Alii: "Indagini Preliminari Sull'attivita Fibrinolitica, Nell'Animale e Nell'Uomo, Di Una Nnuova Sostanza Presente in Diversi Organi Amimali", Simposio Internazional, "La Ricerca Sciefifica in Italia", Roma, Oct. 1975, pp. 557-560 (Proceedings).
R. Niada et Alii: "Antithrombotic Activity of Polydeoxyrbonucleotides of Mammalian Origin (Laboratory Code: Franction P) in Experimental Animals", Thromb. and Haemostas. 42 388, 1979.
G. Prino et Alii: "Antithrobotic Acitivity of a Polydesoxynucleotidic-Like Substance", Extract from volume (A. Strando ed.), Advances in Coagulation, Ibinolysis, Platelet Aggregation and Therosclerosis, European Symposium of S. Flavia Palermo, Oct. 1976), proceedings pp. 282-289.
E. Mozzi et Alii: "Effectiveness of Defibrotide for Prophylaxis of Deep Venous Thrombosis After General Surgery: a Double Lind Placebo-Controlled Clinical Trial", Haemostasis 16, Suppl. 1, pp. 36-38, 1986.
N. Ciavarella et Alii: "Effectiveness of Defibrotide for Prophylaxis of Deep Venous Thrombosis in Gynecological Surgery: a Double-Blind, Placebo-Controlled Clinical Trial", Haemostasis 16, Suppl. 1, pp. 39-41, 1986.
A. Rizz et Alii: "Profilassi Con Defibrotide Delle Bosi Venose Profonde in Chirurgia Toracica", Minerva Medica 78, 745-750, 1987.
R. Niada et Alii: "Antithrobotic Activity of a Polydeoxyribonucleotidic Substance Extracted from Mammalian Organs: a Possible Link with Prostacyclin", Thromb. Res. 23, 233-246, 1981.
J. R. O'Brien et Alii: "The Effect in Humans of Defibrotide I.V. on Mumerous Blood Parameters", Haemostasis, vol. 14, 123, 1984.
L. Mussoni et Alii: "Activation of Plasma and Vasular Fibrinolytic Activity by a Polydeoxyribonucleotidic Substance, Fraction P, in Rats and Rabbits", VII Int. Cong. Thromb. Haem., Thromb. and Haemostas. 42 388, 1979.
A. Kumar et Alii: "Endothlial Function Modulation and Control of Vascular and Thrombotic Disorders: Experimental Results with a Polydeoxyribonucleotide Agent Defibrotide", The American Society of Hematology, 28th Annual Meeting, Dec. 6-9, 1986-San Francisco-Calif., Blood 68 n.5 Suppl. 1, Abstract n. 1302.
A. M. Pogliani et Alii: "Studio di Bioequivalenza di Due Schemi Posologici di Defibrotide su Parametri Della Fibrinolisi in Soggetti Volotari Sani", Farmaci e Terapia, vol. IV, No. 2, 94-98, 1987.
G. Czimeci et Alii: "Corrective Effect of Defibrotide on Altered Endotlium Cell Function in Atherosclerosis", Thromb. and Haemostas. 54 87 1 85.
Crinos Industria Farmacobiologica SPA
Jones W. Gary
LandOfFree
Method for preventing blood coaguli from being formed in the ext does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for preventing blood coaguli from being formed in the ext, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for preventing blood coaguli from being formed in the ext will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1888991