Method for preserving blood using ascorbic acid tocopheryl phosp

Details Method for preserving blood using ascorbic acid tocopheryl phosp Method for preserving blood using ascorbic acid tocopheryl phosp

1994-09-07

1996-01-02

Marx, Irene

Chemistry: molecular biology and microbiology

Maintaining blood or sperm in a physiologically active state...

424529, A01N 102

Patent

active

054807735

ABSTRACT:
A method for the preservation of blood and a blood preserving composition comprising a phosphoric acid diester of the following formula: ##STR1## (wherein R.sub.1 and R.sub.2 are the same or different and each represents a hydrogen atom or a methyl group) or a pharmacologically acceptable salt thereof.
The compounds used for the object of the invention are capable of maintaining the biological function of blood for a long period of time without harming its components. Therefore, the composition of the invention can be advantageously used for preserving blood and its components such as erythrocytes, leukocytes and platelets, and is useful for preventing hepatic disorder which can accompany blood transfusion.

REFERENCES:
patent: 4605644 (1986-08-01), Foker
patent: 4994444 (1991-02-01), Zikria
patent: 5256642 (1993-10-01), Fearon et al.
Kopec-Szlezak J et al, Haematologia 21: 219-226 (1988).

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