Method for preparing unsymmetrical 1,4-dihydropyridine-3,5-dicar

Details Method for preparing unsymmetrical 1,4-dihydropyridine-3,5-dicar Method for preparing unsymmetrical 1,4-dihydropyridine-3,5-dicar

1985-07-09

1988-03-08

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D21190

Patent

active

047300523

ABSTRACT:
Unsymmetrical 1,4-dihydropyridine-3,5-dicarboxylic acid diesters represented by the general formula ##STR1## wherein R.sup.1 and R.sup.2 are different and represent each a nitratoalkyl having 2 or 3 carbon atoms, are prepared from the corresponding acid monoester in the presence of an organic acid anhydride activating agent. These compounds are useful as therapeutic agents for cardiovascular disorders.

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"Derivatives of 1,3-Dimethyl-2-Azafluorene (1,3-Dimethyl-9-Indeno [2,1-c] Pyridine).
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