Drug – bio-affecting and body treating compositions – Extract – body fluid – or cellular material of undetermined... – Blood
Patent
1991-05-21
1993-04-06
Robinson, Douglas W.
Drug, bio-affecting and body treating compositions
Extract, body fluid, or cellular material of undetermined...
Blood
424530, 424531, 424532, 424533, 424534, 514 2, 514 21, A61K 3514, A61K 3516
Patent
active
052001997
ABSTRACT:
A method for isolating tissue repair promoting substances from human or animal blood which comprises collecting the human or animal blood from a single human or animal individual in a first container of a container system comprising at least a first and second interconnected containers; centrifuging the container system containing the blood so as to separate the blood in various fractions including a plasma fraction; transferring at least part of the plasma fraction to the second container of the container system; subjecting the plasma fraction in the second container to a low temperature so as to obtain a precipitate comprising tissue repair promoting substances; concentrating the precipitate in the second container so as to obtain a first fraction comprising a major part of the non-precipitated material; and separating the second fraction comprising the tissue repair promoting substances from said first fraction within the second container; and optionally heating the second fraction within one of the container of the container system so as to dissolve the isolated precipitated tissue repair promoting substances. Furthermore, fractions comprising tissue repair promoting substances derived from blood cells may be isolated within the container system, the fractions optionally being combined with the second fraction comprising tissue repair promoting substances derived from blood plasma. At least part of the fractions obtained may be kept for application to a tissue of the human or animal individual from whom the blood was collected.
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Robinson Douglas W.
Witz Jean C.
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