Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1995-06-06
2000-02-29
Housel, James C.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
4242561, 435 6, 435 723, 435 691, 435 693, 435 711, 435 97, 43523233, 436518, 530350, 530403, 530412, 536 231, 536 237, A61K 39102, C12Q 168, G01N 33574, C12P 2106
Patent
active
060306262
ABSTRACT:
It has been discovered that a vaccine comprised of fimbrin, a filamentous protein derived from the bacterial surface appendages of non-typable Haemophilus influenzae is useful in studying, preventing or reducing the severity of, otitis media. The gene sequence of the DNA coding for fimbrin and the amino acid sequence of fimbrin have also been determined. Vectors containing DNA coding for fimbrin have also been developed, and transformants have been prepared which contain such vectors and which express such DNA and provide a source of pure fimbrin.
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Bakaletz Lauren O.
Kolattukudy Pappachan E.
Sirakova Tatiana
Hines Ja-Na A.
Housel James C.
Ohio State Research Foundation
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