Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form
Reexamination Certificate
2005-04-26
2005-04-26
Page, Thurman K. (Department: 1615)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Particulate form
C424S400000, C424S450000, C264S004000, C264S004100, C264S005000
Reexamination Certificate
active
06884436
ABSTRACT:
The present invention provides a method for preparing a suspension of a pharmaceutically-active compound, the solubility of which is greater in a water-miscible first organic solvent than in a second solvent which is aqueous. The process includes the steps of: (i) dissolving a first quantity of the pharmaceutically-active compound in the water-miscible first organic solvent to form a first solution; (ii) mixing the first solution with the second solvent to precipitate the pharmaceutically-active compound; and (iii) seeding the first solution or the second solvent or the pre-suspension.
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patent:
Brynjelsen Sean
Doty Mark J.
Kipp James E.
Rebbeck Christine L.
Werling Jane
Baxter International Inc.
Fuchs Joseph A.
Mayo Michael C.
Oh Simon J.
Page Thurman K.
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