Method for preparing stable coagulation controls

Details Method for preparing stable coagulation controls Method for preparing stable coagulation controls

1997-09-11

1999-05-25

Pyon, Harold Y.

Chemistry: analytical and immunological testing

Composition for standardization, calibration, simulation,...

Blood serum or blood plasma standard or control

436 8, 436 10, 436 18, 436 69, 435 13, G01N 3386

Patent

active

059069422

ABSTRACT:
A method for preparing a coagulation control sample which is stable in the absence of buffer and which has a clotting time within the range of normal human clotting times for reproducibly monitoring coagulation capability in a human patient comprising (a) collecting blood from a mammalian animal, (b) removing red blood cells from the blood to produce mammalian plasma, and (c) adding to the plasma an amount of at least one non-primate mammalian plasma that has been adsorbed with a coagulation factors II, VII, IX and X adsorbent prior to addition of the plasma to the mammalian plasma.

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