Method for preparing quinoline carboxylic acids and derivatives

Details Method for preparing quinoline carboxylic acids and derivatives Method for preparing quinoline carboxylic acids and derivatives

1994-01-13

1995-07-04

Ivy, C. Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D21522

Patent

active

054301521

ABSTRACT:
A method of preparing substituted and unsubstituted 1,4-dihydro-4-oxo-2 and -3 quinolinic carboxylic acids which comprises heating an ester selected from the group consisting of substituted and unsubstituted anilinomethylenemalonates, anilinofumurates, anilinomaleates and mixutres thereof in the presence of chlorosulfonic acid, oleum and mixtures thereof.

REFERENCES:
patent: 4528287 (1985-07-01), Itoh et al.
Hui-Yuan et al, Pharmaceutical Industry, pp. 390-394, 1986.
Bridges et al., J. Heterocyclic Chemistry, vol. 27, pp. 1527-1536, 1990.

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