Method for preparing pyrrolidine derivatives

Details Method for preparing pyrrolidine derivatives Method for preparing pyrrolidine derivatives

1992-12-24

1994-03-01

Springer, David B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

504283, C07D20726

Patent

active

052909492

ABSTRACT:
The present invention is directed to a method for preparing 3,4-trans-4-ethyl-1,3-disubstituted (substituted phenyl)pyrrolidine-2-one represented by the formula (1) ##STR1## which comprises the steps of dissolving 4-ethyl-1,3-disubstituted (substituted phenyl)-3-pyrroline-2-one in an inert solvent, and then reducing the same with sodium boron hydride in the presence of methanol.

REFERENCES:
patent: 4110105 (1978-08-01), Teach
patent: 4874422 (1989-10-01), Woolard
patent: 4960457 (1990-10-01), Woolard

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