Method for preparing prostaglandin derivative

Details Method for preparing prostaglandin derivative Method for preparing prostaglandin derivative

2007-02-07

2010-10-12

Dentz, Bernard (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C560S121000

Reexamination Certificate

active

07812182

ABSTRACT:
Disclosed is a method for preparing a prostaglandin derivative of formula (A):which comprises reacting an aldehyde represented by formula (1):with a 2-oxoalkyl phosphonate in a reaction solvent under the presence of alkali hydroxide as sole base. By carrying out the reaction using an alkali hydroxide as sole base in the reaction system, the desired prostaglandin derivative can be obtained by simple procedures and with high yield.

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