Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,...
Reexamination Certificate
2006-08-15
2006-08-15
Russel, Jeffrey Edwin (Department: 1654)
Drug, bio-affecting and body treating compositions
Conjugate or complex of monoclonal or polyclonal antibody,...
C424S009340, C514S002600, C514S04400A
Reexamination Certificate
active
07090846
ABSTRACT:
Polycation bioconjugates and a method for producing them. The polycations are capable of transporting active substances of different types. The polycations function as carrier molecules that transport enhancer molecules, thereby enhancing the biological effectiveness of the transported molecules. The polycation bioconjugates of the present invention may inhibit malignant cell proliferation, possess antimicrobial effect, or be configured for gene transport.
REFERENCES:
patent: 4701521 (1987-10-01), Ryser et al.
patent: 4847240 (1989-07-01), Ryser et al.
patent: 5849893 (1998-12-01), Lobberding et al.
patent: 6727347 (2004-04-01), Szego
patent: 38 35 962 (1991-03-01), None
patent: 2212 810 (1989-08-01), None
Ho et al., Improving Emulsifying activity of epsilon-polylysine by conjugation with dextran through the Maillard reaction, Food Chemistry, 68: 449-455 (2000).
Inaki et al., Isopoly-L-Omithine Derivatives of Thymine and Thymidine, Nucleosides & Nucleotides, 17(1-3): 339-350 (1998).
Kricheldorf et al., Binding of Nucleosides to Basic Polypeptides via Isocyanato-isothiocyanates, Die Makromolekulare Chemie, 181: 2571-2585 (1980).
Nosho et al., Synthesis and Antimicrobial Activity of N-alpha-Poly-Acyl-N-Epsilon-Poly-L-Lysine Derivatives, Chemistry Express, 7(10): 753-756 (1992).
Seidenberger, H. et al., “Untersuchungen uber die Zusammenhange zwischen Struktur und Antitumorwirkung bei cis-Dichloro[bis(oligopeptidester)platin-(II)-Komplexen,” Arch. Pharm. (Weinheim) 316(2):121-131 (1983).
Shima et al., Binding of Metal Ions by alpha-Poly-L-Lysine and epsilon-Poly-L-Lysine, Journal of Polymer Science: Polymer Letters Edition, 23: 245-249 (1985).
Shima et al., Polylysine Produced by Streptomyces. Agric. Biol. Chem., 41(9): 1807-1809 (1977).
Uchegbu, I.F. et al., “Polymeric vesicles from amino acid homopolymers,” Proc. Int. Symp. Controlled Release Bioact. Mater., 25: 186-187 (1998).
Refuah Research, Inc.
Russel Jeffrey Edwin
LandOfFree
Method for preparing polycation based bioconjugates suitable... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for preparing polycation based bioconjugates suitable..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for preparing polycation based bioconjugates suitable... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3658025