Method for preparing phosphinic acids used in preparing ace inhi

Details Method for preparing phosphinic acids used in preparing ace inhi Method for preparing phosphinic acids used in preparing ace inhi

1987-09-30

1989-10-10

Howard, Jacqueline V.

Organic compounds -- part of the class 532-570 series

Organic compounds

Phosphorus esters

558179, C07F 932

Patent

active

048733563

ABSTRACT:
A method is provided for preparing phosphinic acid compounds, which are useful in preparing certain angiotensin converting enzyme inhibitors, which have the formula ##STR1## wherein R.sub.1 is lower alkyl, aryl, arylalkyl, cycloalkyl or cycloalkylalkyl;

REFERENCES:
patent: 4396772 (1983-08-01), Petrillo, Jr.
patent: 4448772 (1984-05-01), Karanewsky
patent: 4468519 (1984-08-01), Krapcho

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