Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...
Reexamination Certificate
2009-05-22
2011-11-15
Wilson, James O (Department: 1624)
Organic compounds -- part of the class 532-570 series
Organic compounds
Nitrogen attached directly or indirectly to the purine ring...
Reexamination Certificate
active
08058432
ABSTRACT:
The present invention releates to a method for preparing a phenylalanine compound having a quinazoline-dione ring represented by the following formula (1) or a pharmaceutically acceptable salt thereof:where R1-R4are defined herein. The method involves reacting a specified acyl phenylalanine compound with a carbonyl group-introducing reagent and a specified anthranilic acid compound to form a carboxy-asymmetric urea compound which is converted to a quinazoline-dione compound in the presence of a carboxyl group-activating agent.
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Chinese Office Action issued Jun. 15, 2011.
Fujita Koichi
Kataoka Noriyasu
Okado Kotaro
Okuzumi Tatsuya
Sugiki Masayuki
Ajinomoto Co. Inc.
McDowell Brian
Oblon, Spivak McClelland, Maier & Neustadt, L.L.P.
Wilson James O
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