Method for preparing phenyl acetic acid derivatives

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Reexamination Certificate

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07915421

ABSTRACT:
Method for preparing (S)(+)phenyl acetic acid derivatives having the general formula (I):wherein R1is a linear or branched alkyl group with 1-6 carbon atoms or substituted benzyl group, and R2is methyl, ethyl or propyl group said method, characterised in that a compound of the general formula (II):wherein R1is as given above, and R3is a nucleofuge, or a suitable salt of a compound of the general formula (II) is reacted with a compound having the general formula (III):wherein R2is as given above, and R4is hydrogen or a nucleofuge that can be removed hydrolytically, and the protective group R4that may be present, may be subsequently removed hydrolytically.

REFERENCES:
patent: 5312924 (1994-05-01), Grell et al.
patent: 6143769 (2000-11-01), Grell et al.
patent: 7148355 (2006-12-01), Ray et al.
patent: 2111851 (1993-07-01), None
patent: 0207331 (1987-01-01), None
patent: 0965591 (1999-12-01), None
patent: WO93/00337 (1993-01-01), None
patent: WO2004/018442 (2004-03-01), None
Nucleofuge Web deifinition, chemiPlus p. 1 (2010).
Nucleofuge Web definition, Chem dictionary p. 1 (2010).
Stn. Exhibit I p. 1 (2010).

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