Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound
Reexamination Certificate
2008-05-27
2008-05-27
Ramirez, Delia M (Department: 1652)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing oxygen-containing organic compound
C435S232000, C435S069100, C435S410000, C435S320100, C435S252320, C435S252330, C435S252340, C435S252350, C435S252300, C435S325000, C435S174000
Reexamination Certificate
active
07378261
ABSTRACT:
A biocatalytic method for preparing para-hydroxystyrene from para-hydroxycinnamic acid is described. The method uses an enzyme source having para-hydroxycinnamic acid decarboxylase activity to catalyze the decarboxylation of para-hydroxycinnamic acid in a biphasic reaction medium to produce para-hydroxystyrene, which is extracted into the organic phase of the biphasic reaction medium. The method results in a high yield of para-hydroxystyrene due to the decreased exposure of the enzyme source to the inhibitory product. The product is readily recovered from the extractant, or may be chemically derivatized directly in the extractant before recovery.
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Ben-Bassat Arie
Haynie Sharon L.
Huang Lisa L.
Lowe David J.
E.I. Du Pont de Nemours and Company
Ramirez Delia M
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