Method for preparing nitrogen-containing compounds

Details Method for preparing nitrogen-containing compounds Method for preparing nitrogen-containing compounds

2005-09-20

2005-09-20

O'Sullivan, Peter (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

C564S244000, C564S245000

Reexamination Certificate

active

06946576

ABSTRACT:
A synthesis method which comprises reacting NH group-containing compounds with thiocyanates, cyanamides, nitrites or esters in the presence of a silylating agent to synthesize the corresponding nitrogen-containing addition or substitution products. This method not only enables the direct and efficient synthesis of nitrogen-containing compounds including isothioureas, guanidines, amidines and amides, but it also has a wide range of applications and is suitable for large-scale synthesis.

REFERENCES:
patent: 4379928 (1983-04-01), Theodoropulos
patent: 5114975 (1992-05-01), Boger et al.
patent: 1445 257 (1976-06-01), None
Bambino, Frank et al.,Facile Synthesis of Protected Dipeptide Acids Containing C-Terminal α,α-Dialkyl Amino Acids, Tetrahedron Letters, vol. 32, No. 28, pp. 3407-3408, Great Britain, 1991.
Dukat, Malgorzata et al.,Structure-Activity Relationships for the Binding of Arylpiperazines and Arylbiguanides at 5-HT3Serotonin Receptors, Journal of Med. Chem., vol. 39, pp. 4017-4026, 1996.
Ruhland, T. et al.,Structurally Diverse 2,6-Disubstituted Quinoline Derivatives by Sold-Phase Synthesis, Tetrahedron Letters, vol. 37, No. 16, pp. 2757-2760, 1996, Great Britain.
Tsuji, Kiyoshi et al.,Studies on Anti-Inflammatory Agents. IV.1)Synthesis and Pharmacological Properties of 1,5-Diarylpyrazoles and Related Derivatives, Chem. Pharm. Bulletin, vol. 45(6), pp. 987-995, Jan. 1997.
Wang, Wei-Bo et al.,Tin (II) Amides: New Reagents for the Conversion of Esters to Amides, Journal of Org. Chem., vol. 57 pp. 6101-6103, 1992.

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