Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase
Patent
1990-05-09
1995-08-15
Wax, Robert A.
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Hydrolase
435 691, 4351723, 43525231, 4353201, 536 232, 935 14, 935 27, 935 74, C12N 1500, C12N 1557, C12N 1575
Patent
active
054418828
ABSTRACT:
There are described methods for making mutant subtilisins, the methods comprising obtaining a DNA fragment from a Bacillus subtilisin and introducing a mutation into the fragment by substituting at least one amino acid, transforming a suitable host cell with the mutated DNA, recovering a mutant subtilisin and screening the mutant subtilisin for certain altered enzymatic properties.
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Bott Richard R.
Estell David A.
Wells James A.
Genencor, Inc.
Horn Margaret A.
Moore William W.
Wax Robert A.
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