Method for preparing lipid vesicles

Plastic and nonmetallic article shaping or treating: processes – Encapsulating normally liquid material – Liquid encapsulation utilizing an emulsion or dispersion to...

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424 11, 424 38, 4284022, 436829, B01J 1302, A61K 950

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active

046197958

ABSTRACT:
A method for forming vesicles is described, wherein a lipid coating is formed onto a deformable surface. During hydration, the lipid coating is fragmented by deformation of the surface. The resulting fragments of the lipid coating are dispersed in the hydrating medium, so as to be subjected to multidirectional hydration, whereby formation of vesicles is accelerated. In the preferred embodiment, such surface is defined by a plurality of water-swellable particles formed of a polymeric material.

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patent: 4280816 (1981-07-01), Elahi
patent: 4342826 (1982-08-01), Cole
patent: 4480041 (1984-10-01), Myles et al.
patent: 4485054 (1984-11-01), Mezei et al.

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