Method for preparing free flow resin

Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – Treating polymer containing material or treating a solid...

Reexamination Certificate

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Details

C528S492000, C528S493000, C528S494000, C528S495000, C528S496000, C528S497000, C528S498000

Reexamination Certificate

active

07049394

ABSTRACT:
The present invention provides a method for producing a free flowing and/or non clumping resin that includes prior to drying, shrinking the resin under agitation. In one variant of the invention, the is a resin used in solid phase synthesis of peptides. In another aspect the invention provides a process of making a peptide using the free flowing resin described herein, and a polypeptide made using the process. Various therapeutics are then be made using the polypepdite.

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patent: 62011740 (1987-01-01), None
Su-Sun Wang, “p-Alkoxybenzyl Alcohol Resin and p-Alkoxybenzyloxycarbonylhydrazide Resin for Solid Phase Synthesis of Protected Peptide Fragments”, Journal of the American Chemical Society, 95:4, Feb. 21, 1973, pp. 1328-1333.
Kenneth S. Cameron, et al., “Optimization of Reaction Conditions for REM Resin-Bound Quarternization Reactions”, 2002 American Chemical Society, Mar. 7, 2002, pp. 199-203.
Sunil Rana, et al. “Influence of Resin Cross-Linking on Solid-Phase Chemistry”, 2001 American Chemical Society, Dec. 14, 2000, pp. 9-15.
Harre, et al, “An efficient method for activation and recycling of trityl resins,” Reactive and Functional Polymers, 1999, vol. 41, pp. 111-114, published by Elsevier Science.

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