Method for preparing formylphosphonic acid

Organic compounds -- part of the class 532-570 series – Organic compounds – Phosphorus acids or salts thereof

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558137, C07F 938, C07F 940

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active

060546085

ABSTRACT:
A process for the manufacture of formylphosphonic acid derivatives is reported. An aminomethylphosphonic acid substrate is contacted with a reagent selected from the group consisting of water, an alcohol, a phenol compound, and mixtures thereof and an oxidizing gas in the presence of a catalyst to form a reaction product mixture containing a formylphosphonic acid derivative and the conditions under which said contacting is carried out are controlled so that no more than 50% of the formylphosphonic acid derivative formed in the reaction product mixture is consumed by reaction with the reagent.

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Hamilton, Robert, et al., "The Reaction of Dimethyl Dioxirane with Diazomethylphosphonates; the First Synthesis of A Formylphosphonate Hydrate," J. Chem. Soc., Chem. Commum., pp. 37-38, 1994.
Moedritzer, Kurt, et al., "The Direct Synthesis of .alpha.-Aminomethylphosphonic Acids. Mannich-Type Reactions with Orthophosphorous Acid," Mannich-Type Reactions with Orthophosphorous Acid, vol. 31, pp. 1603-1607, May, 1966.
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Wagenknecht, John, "An Electrochemical Method For The Preparation Of Iminodimethylenediphosphonic Acid," Syn. React. Inorg. Metal-Org. Chem., 4(6), pp. 567-572 (1974).
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CA:91:193420 abs of SU684038, Sep. 1979.

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