Method for preparing fibrinogen adhesive from whole blood

Drug – bio-affecting and body treating compositions – Enzyme or coenzyme containing – Hydrolases

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424530, 514802, A61K 37547, A61K 37553

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active

054056071

ABSTRACT:
A process and apparatus for one-step preparation of the fibrinogen component of an adhesive is described. The fibrinogen is precipitated directly from plasma using polyethylene glycol. This permits preparation of autologous fibrinogen from the patient during surgery which can be combined with calcium, ion and thrombin and used as an adhesive.

REFERENCES:
patent: 4043042 (1977-08-01), Perfect
patent: 4266545 (1981-05-01), Mass
patent: 4298598 (1981-11-01), Schwarz
patent: 4359049 (1982-11-01), Redl et al.
patent: 4362567 (1982-12-01), Schwarz
patent: 4377572 (1983-03-01), Schwarz
patent: 4414976 (1983-11-01), Schwarz
patent: 4427650 (1984-01-01), Stroetmann
patent: 4631055 (1986-12-01), Redl et al.
patent: 4874368 (1989-10-01), Miller et al.
patent: 4902281 (1990-02-01), Avoy
patent: 5030215 (1991-07-01), Morse et al.
patent: 5290552 (1994-03-01), Sierra et al.
Epstein, G. H., et al., "Ann. of Otology, Rhinology and Laryngology" vol. 95, #1, Jan.-Feb. 1986, pp. 40-45.
Masri, M. A., et al., "Thromb. Haemostas (Stuttgert)." vol. 49, #2, 1983, pp. 116-119.
Feldman, M. D., et al., "Arch. Otolcryngel Head Neck Surg." vol. 114, Feb. 1988, pp. 182-185.
Feldman, M. D. et al., "The Amer. J. of Octologoy." vol. 9, #4, Jul. 1988, pp. 302-305.
Feldman, M. D. et al., "Archives of Opthalmology." vol. 105, Sep. 1987, pp. 963-967.
Silberstein, L. E. et al., "Transfusion," vol. 28, 1988, pp. 319-321.
Weisman, R. A., et al., "Laryngoscope," vol. 97, #10, Oct. 1987, pp. 1186-1190.
Staindl, (1979) Ann Otol 88:413-418.
Redl et al., "Biomaterials 1980," Winter, G. D. et al. eds. (1982), pp. 669-676.
Seelich, (1982) J. Head & Neck Pathol., 3:65-69.
O'Connor et al., (1982) Otolaryngol Head Neck Surg. 90:347-348.
Marquet, (1982) J. Head & Neck Pathol. 3:71-72.
Thorson et al., (1983) J. Surg. Oncol. (1983) 2:221-223.
McCarthy et al., (1987) Mayo Clin Pros. 62:317-319.
Portmann, (1982) J. Head & Neck Pathol. 3:96.
Siedentop et al., (1985) Laryngoscope 95:1074-1076.
Kazal et al., (1963) Proc. Sec. Exp. Biol. Med. pp. 989-994.
Mosesson et al., (1986) Biochemistry 5:2829-2835.
Waite et al., (1981) Science 212:1038-1040.
Siedentop et al. (1983) Laryngoscope 93:1310-1313.
Casillas et al., (1982) British J. Haematology 50:665-672.
TISSUCOL, immuno AG, specification sheet, Vienna, Austria.
Redl et al., "Basical Considerations and Theoretical Background of Fibrin Sealing," in European Society for Surgical Research 14th Congress, Barcelona-79.
Sataloff et al., (1987) Laryngoscope 97(9):111-112.
Panis, (1982) J. Head & Neck Pathol. 3:94-95.
Harker et al., (1972) New England Journal of Medicine 287(20):999-1005.

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