Method for preparing disubstituted monochlorotriazines

Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system

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544216, 544219, C07D25126

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active

054461553

ABSTRACT:
Disubstituted monochlorotriazines such as 2-chloro-4-mesitoxy-6-glycidoxy-1,3,5-triazine are prepared in organic solution by first combining a monoorganoxy dichlorotriazine with an aqueous alkali metal hydroxide solution in a specific concentration and molar ratio, and adding to the mixture thus produced a hydroxyaliphatic or hydroxyaromatic compound, preferably glycidol, in the presence of at least one hydrophilic phase transfer catalyst such as tetra-n-butylammonium bromide. The reaction can be integrated with either or both of a prior step of dichlorotriazine preparation and a subsequent step of capping a hydroxy-terminated polymer, especially a polyphenylene ether.

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patent: 5098465 (1992-03-01), Kruger et al.
U.S. patent application Ser. No. 07/795,577, filed Oct. 21, 1991.
"Palmer" in The Structure And Reactions of Heterocyclic Compounds-1967 pp. 98, 99 Edward Arnold (Publishing) Ltd., London.
Alsaidi et al., Synthesis, pp. 921-923 1980.
"Antifungal Drugs", Edited by V. St.Georgiev, Annals of N.Y. Acad. Sci., vol. 544, p. 103, 1988.
"S-Triazines And Derivatives", Interscience Publishers, p. 19, 1959.

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