Method for preparing dicalcium phosphate dihydrate with improved

Details Method for preparing dicalcium phosphate dihydrate with improved Method for preparing dicalcium phosphate dihydrate with improved

1979-05-29

1981-01-27

Vertiz, O. R.

Chemistry of inorganic compounds

With additive

For stabilizing crystal size or shape

423267, 423308, 423311, 424 57, C01B 0000, C01B 1516, C01B 2526

Patent

active

042475260

ABSTRACT:
Dicalcium phosphate dihydrate containing a sufficient amount of trimagnesium phosphate and/or tetrasodium pyrophosphate to inhibit spontaneous hydrolysis and/or decomposition of the dicalcium phosphate dihydrate is widely used as a dental polishing agent with and without added fluoride. Now it has been found that dicalcium phosphate dihydrate containing a sufficient amount of pyrophosphate to provide hydrolytic stability to the dicalcium phosphate can have improved fluoride stability when about 0.1 weight percent to about 5 weight percent of trimagnesium phosphate, and about 0.1 weight percent to about 3 weight percent of at least one pharmaceutically acceptable condensed phosphate salt is added to the formulation. In the preferred embodiment less than 2 percent sodium tripolyphosphate provides satisfactory results.

REFERENCES:
patent: 2852341 (1958-09-01), Bell et al.
patent: 3012852 (1961-12-01), Nelson
patent: 3066056 (1962-11-01), Schlaeger et al.
patent: 3464786 (1969-09-01), Harnisch et al.

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