Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Reexamination Certificate
2005-09-06
2005-09-06
Price, Elvis O. (Department: 1623)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
C514S025000, C514S649000, C514S279000, C514S299000, C514S850000, C536S001110, C536S004100, C536S119000, C536S124000, C560S068000
Reexamination Certificate
active
06939856
ABSTRACT:
The invention pertains to a method for preparing dexchlorpheniramine (“dexchlor”) tannate by reacting dexchlorpheniramine free base at a temperature of about 75 to about 150° C. with tannic acid neat or as an aqueous slurry containing up to about 20 wt. % water. The dexchlorpheniramine free base may be obtained by reacting a commercially available dexchlorpheniramine salt such as dexchlorpheniramine maleate with a base such as aqueous sodium hydroxide. The resultant dexchlor tannate has extended release properties and is useful in pharmaceutical compositions as an antihistamine for human beings.
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Achari Raja G.
Chopdekar Vilas M.
Mellozzi Angelo R.
Redkar Sham N.
Henry Michael C.
Jame Fine Chemicals, Inc.
Matalon Jack
Price Elvis O.
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