Method for preparing d-penicillamine and salts thereof

Details Method for preparing d-penicillamine and salts thereof Method for preparing d-penicillamine and salts thereof

1977-07-08

1979-04-17

Thomas, Jr., James O.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

562557, C07C 9900

Patent

active

041502400

ABSTRACT:
D-Penicillamine and salts thereof may be prepared by reacting certain aryl amines with 4-thiazolidinecarboxylic acid compounds obtained by splitting the .beta.-lactam ring of penicillin derivatives such as benzylpenicillin or phenoxymethylpenicillin.

REFERENCES:
patent: 3888923 (1975-06-01), Asinger et al.
patent: 3960940 (1976-06-01), Elks et al.
Smith, E. Lester, "Methods of Penicillin Assay", pp. 1-5 of a reprint from the Analyst (1948), vol. 73, pp. 197-216, 244-257.

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