Method for preparing cyclic compounds

Details Method for preparing cyclic compounds Method for preparing cyclic compounds

2003-03-26

2008-12-02

Jiang, Shaojia Anna (Department: 1623)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C540S201000, C540S205000, C540S215000, C540S302000, C540S347000

Reexamination Certificate

active

07459551

ABSTRACT:
The present invention provides a method for preparing a β-lactam compound of the following Formula (3), which comprises the step of reacting a compound of the following Formula (1) with a trialkyl phosphite represented by the formula (R5O)3P (wherein R5represents an ethyl group, etc.) in an amount of 2 to 5 moles per mole of the compound and the step of heating the resulting reaction mixture in a diluent, wherein said method is characterized by having the step of completely removing unreacted trialkyl phosphite from the reaction mixture prior to the step of heating.(wherein X represents S, etc., Y represents N, etc., n represents 0 or 1, R1represents an optionally substituted alkyl group containing 1 to 10 carbon atoms, etc., R2and R3each represent an optionally substituted alkyl or heterocyclic group, etc., and R4represents an alkenyloxy group containing 1 to 6 carbon atoms, etc., provided that R1and R2may together form a β-lactam ring, etc.)

REFERENCES:
patent: 212404 (1987-03-01), None
patent: 272747 (1988-07-01), None
patent: 0 399 228 (1990-11-01), None
patent: 597401 (1994-05-01), None
patent: 6422880 (1989-01-01), None
patent: 06 072875 (1994-03-01), None
patent: WO 93 03042 (1993-02-01), None
Battistini et al. “A New Route To Penems And Carbapenems” Tetrahedron Letters, vol. 25, No. 22, 1984, pp. 2395-2398.
Perrone et al. “The Carbonyl-Carbonyl Coupling Route To Penems: A Stepwise Analysis” Tetrahedron Letters, vol. 25, No. 22, 1984, pp. 2399-2402.
Budt et al. “Alkylphosphonous Acid Diesters Novel Reagent For The Oxalimide Cyclisation To Penems” Tetrahedron Letters, vol. 33, No. 37, 1992, pp. 5331-5334.

Affiliated with

Also associated with

Rating

Method for preparing cyclic compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for preparing cyclic compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for preparing cyclic compounds will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4030539