Method for preparing conjugates using polymer maleimides

Details Method for preparing conjugates using polymer maleimides Method for preparing conjugates using polymer maleimides

2010-11-04

2011-11-15

Chu, Yong (Department: 1622)

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

From carboxylic acid or derivative thereof

C525S205000, C526S262000, C526S215000, C526S208000, C526S333000

Reexamination Certificate

active

08058385

ABSTRACT:
Methods for preparing conjugates using polymeric reagents bearing a maleimide are provided. Also provided are compositions comprising the conjugates.

REFERENCES:
patent: 4179337 (1979-12-01), Davis et al.
patent: 4675414 (1987-06-01), DeFusco et al.
patent: 4761460 (1988-08-01), Otsuka et al.
patent: 4775729 (1988-10-01), DeFusco et al.
patent: 5036111 (1991-07-01), Senneron et al.
patent: 5053423 (1991-10-01), Liu
patent: 5166322 (1992-11-01), Shaw et al.
patent: 5585484 (1996-12-01), Acharya et al.
patent: 5629384 (1997-05-01), Veronese et al.
patent: 5641856 (1997-06-01), Meurs
patent: 5648506 (1997-07-01), Desai et al.
patent: 5766897 (1998-06-01), Braxton
patent: 5844020 (1998-12-01), Paine et al.
patent: 5922675 (1999-07-01), Baker et al.
patent: 5932462 (1999-08-01), Harris et al.
patent: 5977163 (1999-11-01), Li et al.
patent: 5990237 (1999-11-01), Bentley et al.
patent: 6180134 (2001-01-01), Zalipsky et al.
patent: 6180598 (2001-01-01), Nelson
patent: 6183738 (2001-02-01), Clark
patent: 6303119 (2001-10-01), Weisgerber et al.
patent: 6362254 (2002-03-01), Harris et al.
patent: 6403753 (2002-06-01), Loy et al.
patent: 6602498 (2003-08-01), Shen
patent: 6673905 (2004-01-01), Pozsgay
patent: 6828401 (2004-12-01), Nho et al.
patent: 6875841 (2005-04-01), Sakanoue et al.
patent: 7432330 (2008-10-01), Kozlowski et al.
patent: 7635734 (2009-12-01), Alferiev et al.
patent: 7872082 (2011-01-01), Kozlowski et al.
patent: 2001/0044526 (2001-11-01), Shen
patent: 2002/0082345 (2002-06-01), Kozlowski et al.
patent: 2003/0065134 (2003-04-01), Sakanoue et al.
patent: 2003/0162693 (2003-08-01), Winslow et al.
patent: 2003/0170474 (2003-09-01), Qiao et al.
patent: 2004/0109841 (2004-06-01), Shen
patent: 2004/0110822 (2004-06-01), McCluskey et al.
patent: 2004/0115165 (2004-06-01), Rosen et al.
patent: 2004/0167287 (2004-08-01), Kozlowski et al.
patent: 2007/0049688 (2007-03-01), Kozlowski et al.
patent: 1 283 233 (2003-02-01), None
patent: 2 031 538 (1970-11-01), None
patent: 02 268155 (1990-11-01), None
patent: 03 012414 (1991-01-01), None
patent: WO 01/68601 (2001-09-01), None
patent: WO 01/84234 (2001-11-01), None
patent: WO 2004/060965 (2004-07-01), None
patent: WO 2005/056636 (2005-06-01), None
Baldwin, et al., “Diastereoselective Diels-Alder Reactions between Substituted 1,3-Butadienes and N-α-Methylbenzylmaleimide”, Tetrahedron Letters, 32(42):5877-5880 (1991).
Booth, et al., “Efficient recognition-induced accerleration of a [3+2] dipolar cycloaddition reaction”, Tetrahedron Letters, 39:6987-6990, (1998).
Bravo, et al., “Synthesis of Polycyclic Systems Via Diels-Alder Reactions of Sugar Derived Dienes”, Heterocycles, 53(1):81-92, (2000).
Brewer, et al., “Evidence for Possible Nonspecific Reactions between N-Ethylmaleimide and Proteins1”, Analytical Biochemistry, 18:248-255, (1967).
Chujo, et al. “Reversible Gelation of Polyoxazoline by Means of Diels-Alder Reaction1”, 23(10):2636-2641, (1990).
Gorin, et al., “Kinetics of the Reaction of N-Ethylmaleimide with Cysteine and Some Congeners”, Archives of Biochemistry and Biophysics, 115:593-597, (1966).
Grigg, et al., “X=Y-ZH Systems as Potential 1,3-Dipoles. Part 11. 1Stereochemistry of 1,3-Dipoles by the Decarboxylative Route to Azomethine Ylides”, J. Chem. Soc. Perkin Trans. I, pp. 2693-2701, (1998).
Harris, et al., “Poly(ethylene glycol) Chemistry and Biological Applications”, ACS Symposium Series, ACS, Washinton D.C., (1997).
Konopíková, et al., “Synthesis and Fungicidal Activity of Isoazolines Fused”, Collect. Czech. Chem. Commun. 57:1521-1536, (1992).
Luo, et al., “Highly Efficient and Thermally Stable Electro-optic Polymer from a Smartly Controlled Crosslinking Process”, 15(19):1635-1638, (2003).
Partis, et al., “Cross-Linking of Protein by ω-Maleimido Alkanoyl N-Hydroxysuccinimido Esters”, J. of Protein Chem., 2(3):263-277, (1983).
Philp, et al., “Recognition-induced control of a Diels-Alder reaction”, Chem. Commu., pp. 879-880, (1998).
Renner, et al., “Allynadic-Imides” J. of Polymer Sci., Part A, 27:1301-1323, (1989).
Shaltout, et al., “Maleimide Functionalized Siloxane Resins”, 576:15-20, (1999).
Smyth, et al., “Reactions of N-Ethylmaleimide with Peptides and Amino Acids”, Biochem. J., 91:589-595, (1964).
International Search Report mailed Feb. 7, 2007, corresponding to PCT Application No. PCT/US2006/028271.
Written Opinion of the International Searching Authority, mailed Feb. 7, 2007, corresponding to PCT Application No. PCT/US2006/028271.
Enzon Pharmaceuticals, Macromolecular Engineering Technologies, pp. 1-14, (2004).
Nektar™—Transforming Therapeutics, Nektar Molecule Engineering: Polyethylene Glycol and Derivatives for Advanced PEGylation, pp. 1-20, Catalog—2003, (Jul. 2003).
Nektar™—Transforming Therapeutics, Nektar Advanced PEGylation: Polyethylene Glycol and Derivatives for Advanced PEGylation, pp. 1-24, Catalog—2004, (Jul. 2004).
NOF Corporation, “PEG Derivatives, Phospholipid and Drug Delivery Materials for Pharmaceuticals”, pp. 1-46, Catalogue 2003—1st, (Jan. 2003).
NOF Corporation, “PEG Derivatives, Phospholipid and Drug Delivery Materials for Pharmaceuticals”, pp. 1-50, Catalogue 2003—2nd, (Mar. 2004).
NOF Corporation, “PEG Derivatives, Phospholipids and Drug Delivery Materials for Pharmaceutical Products and Formulations”, pp. 1-59, Catalogue Ver. 8, (Apr. 2006).
Polypure, Products; PEG amines; PEG acids and amino acids; PEG thiols and disulfides; BIOTINS, (Apr. 2004).
Polypure, Products; PEG amines; PEG acids and amino acids; PEG thiols and disulfides; BIOTINS, (Apr. 2005).
Quanta Biodesign, Labeling, Derivatization and Crosslinking Reagents for Biological and Related Materials with dPEG™, pp. 1-38, (Mar. 12, 2004).
Quanta Biodesign, Labeling, Modification and Crosslinking Reagents incorporating our unique monodispersed dPEG™ Technology, pp. 1-31, (Nov. 5, 2004).
Quanta Biodesign, Ltd., Leading innovator, producer and provider of monodisperse discrete PEG™ (dPEG™) derivatives, (Product Catalog), pp. 1-51, (Updated: Jul. 18, 2005).
Quanta Biodesign, Ltd., Leading innovator, producer and provider of monodisperse discrete PEG™ (dPEG™) derivatives, (Product Catalog), pp. 1-51, (Updated: Nov. 17, 2005).
Shearwater Polymers, Inc., Polyethylene Glycol and Derivatives, pp. 1-49, (Catalog—Mar. 1995).
Shearwater Polymers, Inc., Polyethylene Glycol and Derivatives, pp. 1-53, (Catalog—Jul. 1997).
Shearwater Polymers, Inc., Polyethylene Glycol and Derivatives: Functionalized Biocompatible Polymers for Research and Pharmaceuticals, pp. 1-50, (Catalog—Jan. 2000).
Shearwater Corporation, Polyethylene Glycol and Derivatives for Biomedical Applications, pp. 1-17, (Catalog—Jul. 2001).
Office Communication dated Mar. 2, 2009, corresponding to European Application No. 06 788 037.7-2102.
Office Communication dated May 23, 2008, corresponding to European Application No. 06 788 037.7-2102.
PCT International Preliminary Report on Patentability corresponding to PCT Application No. PCT/US2006/028271 date of mailing Jan. 31, 2008.
Chinese Notification of the First Office Action corresponding to Chinese Patent Application No. 200680034312.8 date of notification Aug. 4, 2010.
Mexican Official Letter corresponding to Mexican Patent Application No. MX/A/2008/000867 dated Jul. 8, 2010.

Affiliated with

Also associated with

Rating

Method for preparing conjugates using polymer maleimides does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for preparing conjugates using polymer maleimides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for preparing conjugates using polymer maleimides will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4272656