Method for preparing closed vesicles

Details Method for preparing closed vesicles Method for preparing closed vesicles

2006-05-23

2006-05-23

Horlick, Kenneth R. (Department: 1637)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

C424S178100

Reexamination Certificate

active

07048944

ABSTRACT:
A method for preparing a closed vesicle by a rehydration of a closed vesicle using a rehydration solution, wherein said closed vesicle comprises a dehydrated micelle particle or dehydrated amphipathic micelle bilayers, preferably a liposome loading a pharmaceutically active substance, and the method is characterized in that the rehydration is carried out at a low temperature such as in the range of from 0° C. to 10° C. The method can provides a rehydrated stable vesicle without a leak of the loaded substance.

REFERENCES:
patent: 4247411 (1981-01-01), Vanlerberghe et al.
patent: 4880635 (1989-11-01), Janoff et al.
patent: 4927571 (1990-05-01), Huang et al.
patent: 5614191 (1997-03-01), Puri
patent: 5616341 (1997-04-01), Mayer
patent: 5817334 (1998-10-01), Schmidt et al.
patent: 6221385 (2001-04-01), Camu et al.
patent: 2069919 (1991-04-01), None
patent: 1305054 (1992-07-01), None
patent: 2069244 (1992-11-01), None
patent: 91/06285 (1991-05-01), None
patent: 92/18104 (1992-10-01), None
patent: 97/04746 (1997-02-01), None
Madden et al., Biochimica et Bipophysica Acta, 817, pp. 67-74 (1985).
Van Bommel et al., International Journal of Pharmaceutics, 22, pp. 299-310 (1984).
Madden et al., Liposomes Rational Design, pp. 261-282 (1999).

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