Method for preparing clopidogrel 1,5-naphthalenedisulfonate...

Details Method for preparing clopidogrel 1,5-naphthalenedisulfonate... Method for preparing clopidogrel 1,5-naphthalenedisulfonate...

2007-03-16

2009-11-03

Morris, Patricia L (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

active

07612207

ABSTRACT:
The present invention relates to a method for preparing clopidogrel 1,5-naphthalenedisulfonate or a hydrate thereof, which comprises reacting a clopidogrel-acid addition salt with disodium 1,5-naphthalenedisulfonate or its hydrate in water, or a mixture of water and an organic solvent. High quality clopidogrel 1,5-naphthalenedisulfonate can be prepared by the inventive method by way of using non-corrosive disodium 1,5-naphthalenedisulfonate.

REFERENCES:
patent: 2005/0256152 (2005-11-01), Doser et al.
patent: 2005099445 (2005-10-01), None
patent: 2005/080890 (2005-09-01), None
patent: 2005/103059 (2005-11-01), None

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