Method for preparing auranofin

Details Method for preparing auranofin Method for preparing auranofin

1977-04-21

1980-04-29

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536122, C07H 2300

Patent

active

042007380

ABSTRACT:
A new synthesis of auranofin comprising reacting 2,3,4,6-tetra-O-acetyl-.alpha.-D-glucopyranosyl bromide with a S-(triethylphosphineaurous)thiouronium salt.

REFERENCES:
patent: 3635945 (1972-01-01), Nemeth et al.
Sutton, "Jour. of Medicinal Chem.," vol. 15, No. 11, 1972, pp. 1095-1098.

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