Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1979-09-20
1981-06-09
Phillips, Delbert R.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
424 88, 424177, C07C10352, A61K 3700
Patent
active
042724333
ABSTRACT:
A method for preparing an antigen comprising a peptide-protein complex which comprises reacting a peptide represented by the general formula (I) ##STR1## wherein m is 0 or 1, as a hapten, with a protein as a carrier in the presence of a dialdehyde represented by the general formula (II)
REFERENCES:
patent: 3794630 (1974-02-01), Mullan et al.
patent: 4075194 (1978-02-01), Sela et al.
Bromer, W., et al., J. Am. Chem. Soc., vol. 79, pp. 2807-2810, 1957.
Chemical Abstracts, vol. 77, 162866d, 1972.
Avraneas, S., et al., Immunochemistry, vol. 6, pp. 53-66, 1966.
Hazel Blondel
Otsuka Pharmaceutical Co. Ltd.
Phillips Delbert R.
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