Method for preparing an implantable multilayer tissue construct

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert

Reexamination Certificate

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C424S093700, C435S177000, C435S180000, C435S395000

Reexamination Certificate

active

06949252

ABSTRACT:
The present invention relates to compositions and methods for preparing tissues or tissue constructs. In selected embodiments, the invention relates to the construction of a multi-layered biological structure (i.e. system) that includes a cellular support matrix seeded with living cells derived from a native tissue. The present invention also relates to tissue culture protocols to promote the in vitro growth of tissues and tissue constructs.

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Richard W. Farndale, et al., A Direct Spectrophotometric Microassay For Sulfated Glycosaminoglycans In Cartilage Cultures,Connective Tissue Research, 9:247-248 (1982).

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