Method for preparing an antitumor dextran using a dextran synthe

Details Method for preparing an antitumor dextran using a dextran synthe Method for preparing an antitumor dextran using a dextran synthe

1995-01-06

1996-01-16

Naff, David M.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

435101, 435 72, 435823, 536112, 536124, C12P 1908, C12P 1904, C08B 3702

Patent

active

054847150

ABSTRACT:
A method is provided for preparing an antitumor dextran by contacting a culture broth containing sucrose with an antitumor dextran obtained from Lactobacillus confusus and collecting the antitumor dextran from the culture broth. The enzyme can be used as a crude enzyme solution or may be further purified by conventional means. The Lactobacillus confusus is preferably one of the following: 40-1 strain (FERM BP-2865) , 40-3 strain (FERM BP-2866) , 77-1 strain (FERM BP-2867), 78-1 strain (FERM BP-2868) or 80-1 strain (FERM BP-2869).

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