Method for preparing .alpha.-(4-isobutylphenyl)propionic acid or

Details Method for preparing .alpha.-(4-isobutylphenyl)propionic acid or Method for preparing .alpha.-(4-isobutylphenyl)propionic acid or

1989-06-19

1992-03-17

Shippen, Michael L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

562406, 562418, 562419, 562496, 568429, 585444, 585445, 585452, 585446, 585467, 585468, 585458, 585464, 585466, C07C 6976

Patent

active

050970615

ABSTRACT:
A method for preparing .alpha.-(4-isobutylphenyl)propionic acid or its precursor is here disclosed which comprises a step A of forming p-isobutylstyrene from p-isobutylethylbenzene and a step B of forming .alpha.-(4-isobutylphenyl)propionaldehyde from p-isobutylstyrene or a step C of forming .alpha.-(4-isobutylphenyl)propionic acid or its alkyl ester from p-isobutylstyrene.
Furthermore, a method for preparing said p-isobutylethylbenzene is also disclosed which comprises alkylating isobutylbenzene or 4-ethyltoluene with ethylene or propylene.

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Olah, "Friedel-Crafts and Related Reactions," vol. II, part 1., pp. 1-37, 116-179 & 259-288 (1964.

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