Method for preparing a topical, aminocaproic acid containing oph

Details Method for preparing a topical, aminocaproic acid containing oph Method for preparing a topical, aminocaproic acid containing oph

1995-05-19

1996-08-20

Kishore, Gollamudi S.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

424428, 424 7804, 514561, 514772, 514912, 514647, 514944, A61K 31195

Patent

active

055476805

ABSTRACT:
A topical gel formulation containing aminocaproic acid prevents secondary hemorrhage following hyphema without the adverse side effects associated with systemically delivered aminocaproic acid. Of ten human patients treated with the formulation, none have experienced a secondary hemorrhage and none have experienced adverse side effects. The topical gel formulation is prepared by a process which ensures sterility, a pH compatible with conditions in the aqueous humor, and optimum consistency. A permeation enhancer such as proparacaine can be incorporated into the gel during formulation and be used to enhance the transport of aminocaproic acid across the corneal epithelium.

REFERENCES:
patent: 4804539 (1989-02-01), Guo
A Uingham et al Archives of Ophthalmology 105, 1987, p. 1421.
A Uingham et al Archives of Ophthalmology 106, 1988 p. 1436.
Ehlers et al Invest--Ophthalmology Vis Science 31, 1990 p. 2389.

Affiliated with

Also associated with

Rating

Method for preparing a topical, aminocaproic acid containing oph does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for preparing a topical, aminocaproic acid containing oph, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for preparing a topical, aminocaproic acid containing oph will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2328683