Drug – bio-affecting and body treating compositions – Dentifrices – Oxygen or chlorine releasing compound containing
Patent
1997-09-05
2000-01-25
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Dentifrices
Oxygen or chlorine releasing compound containing
424 62, 424613, 424660, 433215, 433216, A61K 716, A61K 720, A61K 3322, A61K 3340
Patent
active
06017515&
DESCRIPTION:
BRIEF SUMMARY
The present invention relates to a method for preparing a preparation for bleaching teeth or for treating skin complaints and mucous membrane disorders.
In cosmetic dentistry various products and techniques are used for bleaching both avital and vital teeth. Avital teeth are dead teeth which no longer contain a nerve or contain a nerve which is no longer functioning, for example as a result of a so-called root canal treatment. Vital teeth are live teeth and these do still contain a functioning nerve.
Bleaching of teeth can be carried out, for example, using the product Hi-Lite, which is marketed by Shofu Dental Corporation. This product contains concentrated hydrogen peroxide (35%) as active ingredient and is applied as such to the tooth to be bleached, after which it is allowed to act for 8-10 minutes. During this period bleaching of the tooth takes place as a result of so-called chemical activation.
Bleaching can be accelerated under the influence of light.
In this case the tooth to which the product has been applied is irradiated using a special lamp, as a result of which the period which Is needed for bleaching is shortened to 2-3 minutes. This latter method for bleaching teeth is described in more detail in an article by F. N. Hanosh and G. S. Hanosh in J. Esthet. Dent. 4 (1992) 90-95.
A significant disadvantage of the product Hi-Lite is that it contains the aggressive chemical substance hydrogen peroxide, which, moreover, is present in a high concentration (35%) in the product. The product therefore has to be handled very carefully. When handling this product contact with the skin must also be avoided and it is highly advisable to wear protective gloves and spectacles when handling this product. Furthermore, this product is not found to have a long-lasting bleaching action, that is to say the effect (durability) of the treatment clearly declines after a few months.
Other products, such as Nite-White, which is marketed by New Smile Care-Zahnkosmetik GmbH, contain carba-imide peroxide (CO(NH.sub.2).sub.2.H.sub.2 O.sub.2) as active constituent. According to the prior art, however, it is found that although an appreciable change in colour does occur after active treatment of the tooth to be bleached, this change in colour has virtually completely disappeared after only one week.
No effective agents are disclosed in the prior art for the treatment of skin complaints and mucous membrane disorders, in particular lesions.
The aim of the present invention is to provide a solution to the problems described above by the use of a preparation for bleaching teeth, the preparation containing no aggressive chemical substances. Another aim of the present invention is to provide an effective agent for the treatment of skin complaints and mucous membrane disorders, in particular lesions.
The present invention therefore relates to a method for preparing a preparation for. bleaching teeth or for treating skin complaints and mucous membrane disorders, in which method at least the following are combined: composed of at least a cation A.sup.n+ and an anion O.sub.m X.sup.-, where A is a metal from Group 1 or 2 of the periodic system, n=1 or 2, X is a halogen atom and m=1-4, and being composed of at least a cation A.sup.n+ and an anion [B.sub.p O.sub.q ].sup.r-, where A is a metal from Group 1 or 2 of the periodic system, p=1-4, q=1-8 and r=1-3.
The term gel or paste is used to define materials which 30 have a viscosity and flow characteristics which are comparable with those of a thick, optionally thixotropic, liquid. Examples of such materials are peanut butter, toothpaste, ointments and creams. In this description both terms gel and paste are used alongside one another, it being assumed that the two terms are synonyms of one another. In the formula O.sub.m X.sup.- X can be fluorine, chlorine, bromine or iodine. Examples of the anion O.sub.m X.sup.- are the hypochlorite, hypoiodite, chlorite, iodite, chlorate, bromate, Iodate, perchlorate and periodate anions.
Examples of the anion [B.sub.p O.sub.q ].sup.r- are perborate (B
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Diamond White A.V.V.
Rose Shep K.
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