Method for preparing a powdered particulate composition

Details Method for preparing a powdered particulate composition Method for preparing a powdered particulate composition

1990-12-27

1993-08-24

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

424487, 424488, 424501, 5147726, 514781, 514922, 514974, A61K 914, A61K 3155, A61K 916

Patent

active

052386880

ABSTRACT:
Disclosed are powdered particulates or granules useful for the preparation of certain psychotropic compounds (e.g. mianserin are mirtazepine). The resulting suspensions and relatively tasteless, do not have a local anaesthetic effect and are easy to suspend. The granules contain the psychotropic compound, a cellulose derivative, polymer, and a filler.

REFERENCES:
patent: 4128641 (1978-12-01), Itil
patent: 4284559 (1981-08-01), van der Berg
patent: 4447437 (1984-05-01), Ohnishi et al.
patent: 4623588 (1986-11-01), Nuwayser et al.
patent: 4801460 (1989-01-01), Goertz et al.
patent: 4834985 (1989-05-01), Elger et al.
patent: 4870060 (1989-09-01), Muller
patent: 4938967 (1990-07-01), Newton et al.
Merck Index, 11th Ed, pp. 901, 1375, 769.

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