Method for preparing a direct compression granulated acetaminoph

Details Method for preparing a direct compression granulated acetaminoph Method for preparing a direct compression granulated acetaminoph

1993-09-30

1994-12-06

Cintins, Marianne M.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424465, 424470, 424486, A61K 3105, A61K 926, A61K 4738

Patent

active

053708784

ABSTRACT:
A direct compression granulated acetaminophen tableting composition is prepared by blending acetaminophen with a binder, disintegrant, lubricant and a small amount of water or alcohol, compacting the blend, preferably by roller compacting into sheets, and milling the compacted product into granulated particles of a desired particle size suitable for direct compression tableting.

REFERENCES:
patent: 3424842 (1969-01-01), Nurnberg
patent: 3622677 (1971-11-01), Short et al.
patent: 3639169 (1972-02-01), Brong
patent: 4097606 (1978-06-01), Chavkin et al.
patent: 4439453 (1984-03-01), Vogel
patent: 4551177 (1985-11-01), Trubiano et al.
patent: 4562024 (1985-12-01), Rogerson
patent: 4631284 (1986-12-01), Salpekar et al.
patent: 4820522 (1989-04-01), Radebaugh et al.
patent: 4851230 (1989-07-01), Tencza et al.
patent: 4874757 (1989-10-01), Crawford et al.
patent: 4894236 (1990-01-01), Jang et al.
patent: 4915953 (1990-04-01), Jordan et al.
patent: 4968509 (1990-11-01), Radebaugh et al.
patent: 4983399 (1991-01-01), Maish
patent: 5004613 (1991-04-01), Radebaugh et al.
patent: 5037658 (1991-08-01), Urban et al.
patent: 5130140 (1992-07-01), Urban et al.
patent: 5198228 (1993-03-01), Urban et al.
Falzone et al., Drug Dev Ind Phar 18 (4): 468-489 (1992).

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